Snow cover plays an essential role in regulating the Earth’s climate but it has significant impacts on human well-being in several parts of the world (e.g. source of freshwater for agriculture and human consumption, source of energy for hydroelectric power). In this study the distribution of snow cover variables over the whole Italian territory which includes the southern part of the Alps and the Apennines chain between 2000 and 2022 using MODIS data acquired from Terra and Aqua platform are analyzed. After preprocessing the data to obtain a binary snow/no-snow field, the start (SOS), length (LOS), and end (EOS) of the snow season were calculated. The LOS mean values which range from 0 to 365 days show the highest values over the Alpine chain with a mean value of about 90 days for elevations above 500 m a.s.l. Conversely, the lowest values are seen over the Po Plain area with about 5 days for elevations lower than 500 m a.s.l. Moving to the south, the Apennine region show higher values again for higher elevations with a mean value of 6 days in the West region and to 10 days in the East region. For all regions LOS clearly depends on elevation, but the large variability in values at the same altitude highlights the influence of other factors (e.g., slope, aspect, latitude, and longitude). Regarding the temporal evolution, the east region of the Apennines is the only region where the series shows a significant trend of -3.2 days per decade. When different elevation bands are considered the LOS series shows a significant negative trend only at elevations higher than 3500 m a.s.l. especially due to the signal observed over the Alps of about -5.1 and -0.6 days per decade. To further explore snow cover changes, ERA5-Land reanalysis snow cover was analyzed. A good correlation between MODIS-derived snow metrics and reanalysis over the 21-year period was found. Given this, ERA5-Land snow cover trends across its entire time (1951-2022) was further evaluated, offering a longer-term perspective on snow cover variability in the region.