Nature-based Solutions (NbS) are a promising approach to address challenges related to the implementation of the new EU Nature Restoration Law. However, the ability of NbS to co-generate benefits for human well-being is still insufficiently understood. Therefore, the aim of the project EVESNAT is to evaluate the role of NbS in supporting biodiversity and human well-being under the new EU Nature Restoration Law. Focusing on case study sites in the European Alps, which are located in different ecosystems and with differing social-ecological characteristics, EVESNAT first develops spatially explicit scenarios of NbS adopting a participatory approach. NbS scenarios are aimed to address different issues, including biodiversity enhancement, climate change mitigation, and improvement of resilience and autonomy. By quantifying and comparing multiple key ecosystem services such as provision of food, timbre, and water, mitigation of mountain hazards and heat, climate regulation, recreational opportunities, inspiration, and aesthetic experiences, the project analyses potential impacts and benefits, as well as synergies and trade-offs among ecosystem services across NbS scenarios, in addition to assessing the results in terms of biodiversity co-benefits. The findings of the project EVESNAT will contribute to an improved management and governance supporting the targets of the Nature Restoration Law and provide a knowledge base with general guidelines and concrete examples of NbS supporting biodiversity conservation and assuring the provision of multiple ecosystem services.