This study investigates the resilience of the Wakhi community in High Mountain Asia, analyzing the multifaceted challenges posed by disasters through the lens of spatial, temporal, political, cultural, and environmental liminality, as well as Actor-Network Theory (ANT) and Foucauldian Discourse Analysis (FDA). The Pamirian Knot, a geographical threshold between South and Central Asia, embodies spatial liminality, where the region’s landscape exacerbates hazardous events such as floods, avalanches and landslides. Temporally, the Wakhi’s historical experiences at the crossroads of empires and state building processes highlight their adaptive responses to external pressures and disaster events. Culturally, the community navigates the balance between Indigenous Knowledge and modern disaster management strategies. Politically, shifting geopolitical interests and varying governance structures across four countries influence disaster response and community dynamics. Environmentally, climate change exacerbates hazardous events, heightening community fears and transforming risk landscapes. By applying ANT, this study maps the relational networks that shape disaster resilience, emphasizing the interplay between human actors (e.g., organizations, government, community groups) and non-human actors (e.g., climate change, infrastructure, technologies). Through FDA, it critiques dominant disaster management discourses, highlighting how colonial and post-colonial narratives marginalize the Wakhi’s Indigenous Knowledge. The research underscores the need to reclaim Indigenous practices and promoting culturally sensitive approaches to enhance resilience. Through detailed case studies of specific disasters, the study illustrates community responses and outcomes, offering insights into effective practices for disaster risk communication and resilience. The findings emphasize the need for integrated approaches that consider all dimensions of liminality, networked interactions and discursive power dynamics to support the Wakhi community’s resilience. This study contributes to the broader understanding of disaster resilience in marginalized regions advocating for policies and practices that empower local communities and respect their cultural heritage. Future research should continue to explore the interconnectedness of these factors and promote interdisciplinary and participatory approaches to studying disaster resilience.