Significant advances in adaptation to CC in the Andes have been made over the past two decades, but we still face challenges on several key fronts, including the analysis of the strategies that have been implemented so far, in order to assess their effectiveness and promote true adaptive management strategies. We present a study of the current state of adaptation solutions in the Andes, with a comparative analysis of 40 measures implemented along the range in a wide diversity of socio-environmental contexts, from the humid páramos of the northern Andes to the dry punas of the altiplano. The study offers a window into the path taken by adaptation to CC in the Andes in recent, years in terms of their geographical distribution and working ecosystems, the thematic approaches developed, the type of actors involved, their requirements in terms of human and financial resources, and their implementation timeframes. We show how solutions often share features such as significant community participation, but also illustrate different realities in terms of the duration and depth of adaptation processes in the territory, their articulation with national programs and policies, or the effective use of monitoring and evaluation strategies for their environmental and social impacts.